Mediterranean cruises are a spectacular way to explore the rich history, diverse cultures, and stunning coastlines of Europe. Cruise ships typically depart from iconic ports such as Barcelona, Rome (Civitavecchia), Venice, and Athens (Piraeus), all of which are easily accessible by international flights, trains, or local transport. Leading cruise lines like MSC Cruises, Royal Caribbean, Norwegian Cruise Line, Celebrity Cruises, and Viking offer itineraries that cover breathtaking destinations from the French Riviera to the Greek Islands. These cruises often combine vibrant cities with picturesque coastal villages, creating a perfect blend of relaxation and exploration. Whether you’re seeking luxury or family-friendly adventures, Mediterranean cruises offer something for everyone.
Ship: Queen Anne
Nights: 8
Itinerary: Rome (civitavecchia), La Spezia, Marseille, Malaga, Gibraltar, Southampton;
Single
$ 19,828
Twin
$ 10,044
Triple
sold out
Quad
sold out
Ship: Celebrity Equinox
Nights: 10
Itinerary: Barcelona, Valletta, Athens (piraeus), Ephesus (kusadasi), Santorini, Mykonos, Katakolon, Rome (civitavecchia);
Single
$ 4,839
Twin
$ 2,706
Triple
$ 2,275
Quad
$ 2,053
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,272
Twin
$ 2,345
Triple
$ 2,027
Quad
$ 1,863
Ship: Brilliance Of The Seas
Nights: 7
Itinerary: Barcelona, Provence (toulon), Ajaccio, Rome (civitavecchia), Naples, Sicily (messina);
Single
$ 3,448
Twin
$ 1,894
Triple
$ 1,640
Quad
$ 1,511
Ship: Queen Victoria
Nights: 7
Itinerary: Rome (civitavecchia), Marseille, Villefranche, Genoa, La Spezia, Rome (civitavecchia);
Single
$ 2,892
Twin
$ 1,800
Triple
$ 1,626
Quad
$ 1,492
Ship: Queen Victoria
Nights: 14
Itinerary: Rome (civitavecchia), Marseille, Villefranche, Genoa, La Spezia, Rome (civitavecchia), Messina Strait, Rhodes, Ephesus (kusadasi), Dardanelles, Istanb
Single
$ 6,588
Twin
$ 3,893
Triple
$ 3,686
Quad
$ 3,393
Ship: Queen Victoria
Nights: 21
Itinerary: Rome (civitavecchia), Marseille, Villefranche, Genoa, La Spezia, Rome (civitavecchia), Messina Strait, Rhodes, Ephesus (kusadasi), Dardanelles, Istanb
Single
$ 9,916
Twin
$ 5,742
Triple
$ 5,093
Quad
$ 4,685
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia);
Single
$ 4,025
Twin
$ 2,233
Triple
$ 1,870
Quad
$ 1,655
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, R
Single
$ 7,830
Twin
$ 4,329
Triple
$ 3,628
Quad
$ 3,202
Ship: -
Nights: 10
Itinerary: Rome (civitavecchia), Sicily (messina), Katakolon, Corfu, Dubrovnik, Split, Naples, Rome (civitavecchia);
Single
$ 4,954
Twin
$ 3,574
Triple
$ 2,890
Quad
$ 2,540
Ship: -
Nights: 7
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia);
Single
$ 3,873
Twin
$ 2,373
Triple
$ 1,992
Quad
$ 1,726
Ship: -
Nights: 14
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 9,058
Twin
$ 4,979
Triple
$ 4,224
Quad
$ 3,694
Ship: -
Nights: 21
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Corfu, Messina,
Single
$ 13,574
Twin
$ 7,434
Triple
$ 6,255
Quad
$ 5,442
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,045
Twin
$ 2,228
Triple
$ 1,942
Quad
$ 1,794
Ship: Celebrity Constellation
Nights: 11
Itinerary: Rome (civitavecchia), Florence/pisa(livorno), Florence/pisa(livorno), Amalfi Coast (salerno), Sicily (messina), Kotor, Dubrovnik, Split, Zadar;
Single
$ 5,908
Twin
$ 3,186
Triple
$ 2,601
Quad
$ 2,309
Ship: -
Nights: 11
Itinerary: Barcelona, Seville (cadiz), Lisbon, Madeira (funchal), Madeira (funchal), Tangier, Palma De Mallorca, Barcelona;
Single
$ 5,653
Twin
$ 3,863
Triple
$ 3,131
Quad
$ 2,757
Ship: Queen Victoria
Nights: 14
Itinerary: Rome (civitavecchia), Messina Strait, Rhodes, Ephesus (kusadasi), Dardanelles, Istanbul, Istanbul, Dardanelles, Athens (piraeus), Santorini, Olympia (
Single
$ 6,282
Twin
$ 3,605
Triple
$ 3,251
Quad
$ 2,991
Ship: Queen Victoria
Nights: 7
Itinerary: Rome (civitavecchia), Messina Strait, Rhodes, Ephesus (kusadasi), Dardanelles, Istanbul, Istanbul;
Single
$ 3,251
Twin
$ 1,894
Triple
$ 1,854
Quad
sold out
Ship: Queen Victoria
Nights: 25
Itinerary: Rome (civitavecchia), Messina Strait, Rhodes, Ephesus (kusadasi), Dardanelles, Istanbul, Istanbul, Dardanelles, Athens (piraeus), Santorini, Olympia (
Single
$ 9,968
Twin
$ 5,780
Triple
$ 5,421
Quad
$ 4,987
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, Rome (civitavecchia);
Single
$ 3,993
Twin
$ 2,216
Triple
$ 1,853
Quad
$ 1,638
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), R
Single
$ 7,812
Twin
$ 4,342
Triple
$ 3,643
Quad
$ 3,220
Ship: Celebrity Equinox
Nights: 9
Itinerary: Rome (civitavecchia), Naples, Florence/pisa(laspezia)italy, Florence/pisa(laspezia)italy, Portofino, Nice (villefranche), Provence(marseilles), Barcel
Single
$ 4,987
Twin
$ 2,685
Triple
$ 2,192
Quad
$ 1,937
Ship: -
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 4,079
Twin
$ 2,530
Triple
$ 2,130
Quad
$ 1,853
Ship: -
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Corfu, Messina, Capri/naples, Barcelona;
Single
$ 9,075
Twin
$ 4,971
Triple
$ 4,173
Quad
$ 3,628
Ship: -
Nights: 21
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Corfu, Messina, Capri/naples, Barcelona, Gibraltar, Mar
Single
$ 13,371
Twin
$ 7,310
Triple
$ 6,147
Quad
$ 6,078
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,119
Twin
$ 2,260
Triple
$ 1,959
Quad
$ 1,803
Ship: Brilliance Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Naples, Sicily (messina), Santorini, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 3,861
Twin
$ 2,137
Triple
$ 1,820
Quad
$ 1,658
Ship: -
Nights: 11
Itinerary: Rome (civitavecchia), Chania (souda), Santorini, Ephesus (kusadasi), Istanbul, Istanbul, Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,944
Twin
$ 3,791
Triple
$ 3,136
Quad
$ 2,801
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia);
Single
$ 3,977
Twin
$ 2,222
Triple
$ 1,871
Quad
$ 1,658
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, R
Single
$ 7,967
Twin
$ 4,407
Triple
$ 3,696
Quad
$ 3,265
Ship: Celebrity Equinox
Nights: 9
Itinerary: Barcelona, Lisbon, Lisbon, Porto (leixoes), Seville (cadiz), Tangier, Barcelona;
Single
$ 4,079
Twin
$ 2,241
Triple
$ 1,856
Quad
$ 1,661
Ship: -
Nights: 10
Itinerary: Barcelona, Naples, Sicily (messina), Rome (civitavecchia), Portofino, Florence/pisa(laspezia)italy, Nice (villefranche), Barcelona;
Single
$ 5,483
Twin
$ 3,862
Triple
$ 2,969
Quad
$ 2,514
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,166
Twin
$ 2,282
Triple
$ 1,962
Quad
$ 1,798
Ship: Queen Victoria
Nights: 11
Itinerary: Rome (civitavecchia), Mallorca (palma), Cartagena, Malaga, Lisbon, La Coruna, Southampton;
Single
$ 3,508
Twin
$ 2,278
Triple
$ 2,208
Quad
$ 2,029
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, Rome (civitavecchia);
Single
$ 4,142
Twin
$ 2,288
Triple
$ 1,922
Quad
$ 1,684
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), R
Single
$ 7,869
Twin
$ 4,361
Triple
$ 3,655
Quad
$ 3,227
Ship: -
Nights: 10
Itinerary: Rome (civitavecchia), Sicily (messina), Katakolon, Corfu, Dubrovnik, Split, Naples, Rome (civitavecchia);
Single
$ 4,768
Twin
$ 3,427
Triple
$ 2,773
Quad
$ 2,439
Ship: -
Nights: 7
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia);
Single
$ 3,994
Twin
$ 2,443
Triple
$ 2,056
Quad
$ 1,780
Ship: -
Nights: 14
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 8,897
Twin
$ 4,891
Triple
$ 4,133
Quad
$ 3,612
Ship: -
Nights: 21
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Corfu, Messina,
Single
$ 13,428
Twin
$ 7,347
Triple
$ 6,212
Quad
$ 5,397
Ship: Celebrity Equinox
Nights: 10
Itinerary: Barcelona, Valletta, Sicily (messina), Naples, Rome (civitavecchia), Florence/pisa(laspezia)italy, Nice (villefranche), Barcelona;
Single
$ 4,668
Twin
$ 2,554
Triple
$ 2,115
Quad
$ 1,888
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Sicily (messina), Santorini, Mykonos, Naples, Rome (civitavecchia);
Single
$ 3,979
Twin
$ 2,157
Triple
$ 1,849
Quad
$ 1,693
Ship: Celebrity Constellation
Nights: 11
Itinerary: Rome (civitavecchia), Florence/pisa(livorno), Florence/pisa(livorno), Amalfi Coast (salerno), Sicily (messina), Kotor, Dubrovnik, Split, Zadar;
Single
$ 5,335
Twin
$ 2,891
Triple
$ 2,367
Quad
$ 2,105
Ship: -
Nights: 11
Itinerary: Barcelona, Seville (cadiz), Lisbon, Madeira (funchal), Madeira (funchal), Tangier, Palma De Mallorca, Barcelona;
Single
$ 5,647
Twin
$ 4,010
Triple
$ 3,249
Quad
$ 2,860
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia);
Single
$ 4,021
Twin
$ 2,249
Triple
$ 1,830
Quad
$ 1,620
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, R
Single
$ 7,804
Twin
$ 4,333
Triple
$ 3,630
Quad
$ 3,204
Ship: -
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 4,117
Twin
$ 2,537
Triple
$ 2,149
Quad
$ 1,869
Ship: -
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Corfu, Messina, Capri/naples, Barcelona;
Single
$ 9,104
Twin
$ 4,996
Triple
$ 4,164
Quad
$ 3,623
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Sicily (messina), Santorini, Mykonos, Naples, Rome (civitavecchia);
Single
$ 3,819
Twin
$ 2,074
Triple
$ 1,787
Quad
$ 1,641
Ship: Brilliance Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Naples, Sicily (messina), Valletta, Dubrovnik, Split;
Single
$ 3,632
Twin
$ 1,980
Triple
$ 1,678
Quad
$ 1,525