Mediterranean cruises are a spectacular way to explore the rich history, diverse cultures, and stunning coastlines of Europe. Cruise ships typically depart from iconic ports such as Barcelona, Rome (Civitavecchia), Venice, and Athens (Piraeus), all of which are easily accessible by international flights, trains, or local transport. Leading cruise lines like MSC Cruises, Royal Caribbean, Norwegian Cruise Line, Celebrity Cruises, and Viking offer itineraries that cover breathtaking destinations from the French Riviera to the Greek Islands. These cruises often combine vibrant cities with picturesque coastal villages, creating a perfect blend of relaxation and exploration. Whether you’re seeking luxury or family-friendly adventures, Mediterranean cruises offer something for everyone.
Ship: Celebrity Equinox
Nights: 9
Itinerary: Rome (civitavecchia), Naples, Florence/pisa(laspezia)italy, Florence/pisa(laspezia)italy, Portofino, Nice (villefranche), Provence(marseilles), Barcel
Single
$ 4,716
Twin
$ 2,545
Triple
$ 2,080
Quad
$ 1,839
Ship: -
Nights: 10
Itinerary: Rome (civitavecchia), Sicily (messina), Split, Dubrovnik, Corfu, Katakolon, Naples, Rome (civitavecchia);
Single
$ 4,930
Twin
$ 3,577
Triple
$ 2,894
Quad
$ 2,545
Ship: -
Nights: 7
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia);
Single
$ 3,977
Twin
$ 2,429
Triple
$ 2,070
Quad
$ 1,811
Ship: -
Nights: 14
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 8,655
Twin
$ 4,751
Triple
$ 4,026
Quad
$ 3,543
Ship: -
Nights: 21
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Santorini, Corf
Single
$ 13,702
Twin
$ 7,481
Triple
$ 7,396
Quad
$ 7,413
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,335
Twin
$ 2,373
Triple
$ 2,053
Quad
$ 1,888
Ship: -
Nights: 7
Itinerary: Barcelona, Palma De Mallorca, Provence(marseilles), Florence/pisa(laspezia)italy, Rome (civitavecchia), Naples, Barcelona;
Single
$ 3,825
Twin
$ 2,065
Triple
$ 1,782
Quad
$ 1,638
Ship: Celebrity Constellation
Nights: 11
Itinerary: Rome (civitavecchia), Florence/pisa(livorno), Florence/pisa(livorno), Amalfi Coast (salerno), Sicily (messina), Kotor, Dubrovnik, Split, Zadar;
Single
$ 5,622
Twin
$ 3,039
Triple
$ 2,484
Quad
$ 2,207
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia);
Single
$ 4,017
Twin
$ 2,233
Triple
$ 1,880
Quad
$ 1,662
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, R
Single
$ 7,681
Twin
$ 4,256
Triple
$ 3,554
Quad
$ 3,131
Ship: Celebrity Equinox
Nights: 9
Itinerary: Barcelona, Seville (cadiz), Lisbon, Lisbon, Porto (leixoes), Tangier, Barcelona;
Single
$ 5,027
Twin
$ 2,725
Triple
$ 2,236
Quad
$ 1,983
Ship: -
Nights: 7
Itinerary: Barcelona, Valletta, Ephesus (kusadasi), Mykonos, Santorini, Athens (piraeus);
Single
$ 4,473
Twin
$ 2,788
Triple
$ 2,298
Quad
$ 2,054
Ship: -
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 3,902
Twin
$ 2,408
Triple
$ 2,037
Quad
$ 1,777
Ship: -
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Santorini, Corfu, Messina, Barcelona;
Single
$ 9,058
Twin
$ 4,952
Triple
$ 4,975
Quad
$ 4,415
Ship: -
Nights: 21
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Santorini, Corfu, Messina, Barcelona, Gibraltar, Marsei
Single
$ 13,417
Twin
$ 7,307
Triple
$ 6,237
Quad
$ 6,391
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,190
Twin
$ 2,299
Triple
$ 2,003
Quad
$ 1,850
Ship: Brilliance Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Florence/pisa(livorno), Santa Margarita, Nice (villefranche), Provence(marseilles), Valencia, Barcelona;
Single
$ 3,763
Twin
$ 2,050
Triple
$ 1,750
Quad
$ 1,597
Ship: Queen Victoria
Nights: 14
Itinerary: Barcelona, Toulon, Florence/pisa (livorno), Ibiza, Valencia, Barcelona, Alghero, Ajaccio, Messina Strait, Messina, Salerno, Rome (civitavecchia);
Single
$ 4,901
Twin
$ 3,381
Triple
$ 3,106
Quad
$ 2,857
Ship: Queen Victoria
Nights: 7
Itinerary: Barcelona, Toulon, Florence/pisa (livorno), Ibiza, Valencia, Barcelona;
Single
$ 3,086
Twin
$ 1,800
Triple
$ 1,626
Quad
$ 1,492
Ship: Queen Victoria
Nights: 21
Itinerary: Barcelona, Toulon, Florence/pisa (livorno), Ibiza, Valencia, Barcelona, Alghero, Ajaccio, Messina Strait, Messina, Salerno, Rome (civitavecchia), Mess
Single
$ 8,069
Twin
$ 4,840
Triple
$ 4,416
Quad
$ 4,060
Ship: -
Nights: 11
Itinerary: Rome (civitavecchia), Chania (souda), Ephesus (kusadasi), Istanbul, Istanbul, Santorini, Mykonos, Naples, Rome (civitavecchia);
Single
$ 5,131
Twin
$ 3,952
Triple
$ 3,274
Quad
$ 2,928
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, Rome (civitavecchia);
Single
$ 3,771
Twin
$ 2,105
Triple
$ 1,769
Quad
$ 1,559
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), R
Single
$ 7,583
Twin
$ 4,210
Triple
$ 3,519
Quad
$ 3,101
Ship: Celebrity Equinox
Nights: 10
Itinerary: Barcelona, Valletta, Athens (piraeus), Ephesus (kusadasi), Santorini, Mykonos, Katakolon, Rome (civitavecchia);
Single
$ 4,839
Twin
$ 2,706
Triple
$ 2,275
Quad
$ 2,053
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,160
Twin
$ 2,283
Triple
$ 1,992
Quad
$ 1,842
Ship: Brilliance Of The Seas
Nights: 7
Itinerary: Barcelona, Provence (toulon), Ajaccio, Rome (civitavecchia), Naples, Sicily (messina);
Single
$ 3,612
Twin
$ 1,978
Triple
$ 1,719
Quad
$ 1,588
Ship: Queen Victoria
Nights: 7
Itinerary: Barcelona, Alghero, Ajaccio, Messina Strait, Messina, Salerno, Rome (civitavecchia);
Single
$ 3,251
Twin
$ 1,894
Triple
$ 1,748
Quad
$ 1,605
Ship: Queen Victoria
Nights: 14
Itinerary: Barcelona, Alghero, Ajaccio, Messina Strait, Messina, Salerno, Rome (civitavecchia), Messina Strait, Cephalonia, Corfu, Kotor, Split, Trieste;
Single
$ 6,029
Twin
$ 3,614
Triple
$ 3,251
Quad
$ 2,991
Ship: Queen Victoria
Nights: 21
Itinerary: Barcelona, Alghero, Ajaccio, Messina Strait, Messina, Salerno, Rome (civitavecchia), Messina Strait, Cephalonia, Corfu, Kotor, Split, Trieste, Zadar,
Single
$ 9,526
Twin
$ 5,519
Triple
$ 4,948
Quad
$ 4,551
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia);
Single
$ 3,938
Twin
$ 2,196
Triple
$ 1,844
Quad
$ 1,631
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, R
Single
$ 7,628
Twin
$ 4,227
Triple
$ 3,679
Quad
$ 3,225
Ship: -
Nights: 10
Itinerary: Rome (civitavecchia), Corfu, Katakolon, Dubrovnik, Split, Sicily (messina), Naples, Rome (civitavecchia);
Single
$ 5,133
Twin
$ 3,722
Triple
$ 3,007
Quad
$ 2,642
Ship: -
Nights: 7
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia);
Single
$ 3,745
Twin
$ 2,298
Triple
$ 1,952
Quad
$ 1,703
Ship: -
Nights: 14
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 8,331
Twin
$ 4,583
Triple
$ 3,884
Quad
$ 3,419
Ship: -
Nights: 21
Itinerary: Barcelona, Gibraltar, Marseille, Genoa, Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Santorini, Corf
Single
$ 12,461
Twin
$ 6,850
Triple
$ 6,683
Quad
$ 6,409
Ship: -
Nights: 7
Itinerary: Barcelona, Nice (villefranche), Portofino, Florence/pisa(laspezia)italy, Rome (civitavecchia), Naples, Barcelona;
Single
$ 3,525
Twin
$ 2,410
Triple
$ 1,974
Quad
$ 1,748
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,132
Twin
$ 2,269
Triple
$ 1,983
Quad
$ 1,835
Ship: -
Nights: 7
Itinerary: Barcelona, Palma De Mallorca, Florence/pisa(laspezia)italy, Rome (civitavecchia), Naples, Barcelona;
Single
$ 4,026
Twin
$ 2,155
Triple
$ 1,855
Quad
$ 1,703
Ship: Celebrity Constellation
Nights: 11
Itinerary: Rome (civitavecchia), Florence/pisa(livorno), Florence/pisa(livorno), Amalfi Coast (salerno), Sicily (messina), Kotor, Dubrovnik, Split, Zadar;
Single
$ 5,622
Twin
$ 3,038
Triple
$ 2,484
Quad
$ 2,206
Ship: Queen Victoria
Nights: 14
Itinerary: Rome (civitavecchia), Messina Strait, Cephalonia, Corfu, Kotor, Split, Trieste, Zadar, Dubrovnik, Valletta, Capri/naples, Rome (civitavecchia);
Single
$ 5,521
Twin
$ 3,753
Triple
$ 3,493
Quad
$ 3,214
Ship: Queen Victoria
Nights: 7
Itinerary: Rome (civitavecchia), Messina Strait, Cephalonia, Corfu, Kotor, Split, Trieste;
Single
$ 3,221
Twin
$ 1,988
Triple
$ 1,789
Quad
$ 1,643
Ship: Queen Victoria
Nights: 21
Itinerary: Rome (civitavecchia), Messina Strait, Cephalonia, Corfu, Kotor, Split, Trieste, Zadar, Dubrovnik, Valletta, Capri/naples, Rome (civitavecchia), Marsei
Single
$ 9,314
Twin
$ 5,398
Triple
$ 4,948
Quad
$ 4,551
Ship: Enchanted Princess
Nights: 7
Itinerary: Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, Rome (civitavecchia);
Single
$ 3,803
Twin
$ 2,122
Triple
$ 1,785
Quad
$ 1,575
Ship: Enchanted Princess
Nights: 14
Itinerary: Rome (civitavecchia), Corfu, Dubrovnik, Kotor, Capri/naples, Rome (civitavecchia), Capri/naples, Santorini, Ephesus (kusadasi), Olympia (katakolon), R
Single
$ 7,690
Twin
$ 4,254
Triple
$ 3,546
Quad
$ 3,125
Ship: Celebrity Equinox
Nights: 9
Itinerary: Rome (civitavecchia), Naples, Portofino, Florence/pisa(laspezia)italy, Florence/pisa(laspezia)italy, Nice (villefranche), Provence(marseilles), Barcel
Single
$ 5,008
Twin
$ 2,697
Triple
$ 2,199
Quad
$ 1,943
Ship: -
Nights: 7
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus);
Single
$ 3,824
Twin
$ 2,361
Triple
$ 2,022
Quad
$ 1,770
Ship: -
Nights: 14
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Santorini, Corfu, Messina, Barcelona;
Single
$ 8,396
Twin
$ 4,619
Triple
$ 4,718
Quad
$ 4,168
Ship: -
Nights: 21
Itinerary: Rome (civitavecchia), Capri/naples, Soudha Bay, Ephesus (kusadasi), Mykonos, Athens (piraeus), Santorini, Corfu, Messina, Barcelona, Gibraltar, Marsei
Single
$ 12,185
Twin
$ 6,689
Triple
$ 5,708
Quad
$ 6,556
Ship: -
Nights: 7
Itinerary: Barcelona, Provence(marseilles), Portofino, Florence/pisa(laspezia)italy, Rome (civitavecchia), Naples, Barcelona;
Single
$ 3,421
Twin
$ 2,543
Triple
$ 2,078
Quad
$ 1,838
Ship: Odyssey Of The Seas
Nights: 7
Itinerary: Rome (civitavecchia), Santorini, Ephesus (kusadasi), Mykonos, Naples, Rome (civitavecchia);
Single
$ 4,116
Twin
$ 2,258
Triple
$ 1,977
Quad
$ 1,831